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Important

Principles 

By using the website www.bellevue.ch, you confirm that you have read, understood and accepted the general information provided by the Bellevue Group AG as well as these legal provisions. These may be subject to change and the use of the site may be restricted or terminated at any time without prior notice.

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The information, products, data, services, tools and documents contained or described on this site ("website content") are for information purposes only and constitute neither an advertisement or recommendation nor an offer or solicitation (to buy) or redemption (sell) investment instruments, to effect any transaction or to enter into any legal relations.

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The financial products mentioned on this site are not suitable for all investors. The information contained on this site does not constitute a financial, legal, fiscal or any other recommendation. Investment or other decisions should not be made solely on the basis of this document. In particular, you should not enter into any investment before you have read the corresponding fund agreement or legal prospectus, the annual and semi-annual reports, the articles of association (as far as they are applicable), as well as all other documents, as required in accordance with local legislation or the regulations applied in the legal jurisdictions or countries in which the corresponding investment fund has been licensed or approved for public offer or sale to the public.

In order to determine whether the investment in shares of a certain investment fund meets your specific requirements and matches your envisaged risks, we recommend that you contact an independent financial adviser. Furthermore, we recommend that you consult an independent tax adviser in order to obtain information on the tax regulations relating to a specific investment in your legal jurisdiction and with regard to your personal circumstances. In particular tax treatment depends on individual circumstances and may be subject to change.

As the funds are recognised (ie. registered) but not authorised in the UK, the UK Financial Services Authority's financial services compensation scheme does not apply to investments in the fund but the Financial Services Authority regulated firm approving this document for the purposes of UK regulation has taken reasonable steps to satisfy itself that Bellevue will deal in an honest and reliable way and is so satisfied.

Performance

Past performance is not an indication or guarantee of the future performance of the investment. The value of investments may be subject to fluctuations and, under certain circumstances, investors may not get back the full amount invested. The performance data are calculated without taking account of commissions and costs that result from subscriptions and redemptions and commissions and costs have a negative impact on performance. Changes in foreign-exchange rates may also cause the value of investments to go up or down.

Target group of the sites 

The sites are intended exclusively for use by legal entities and natural persons having their registered office or residing in countries in which the investment funds or the related subfunds or share classes of the Bellevue Group have been properly licensed or approved for public offer or sale in accordance with the applicable local legislation. The funds are currently registered for public distribution offer in the following countries: Luxembourg, Switzerland, Germany, Austria, Spain and Portugal. In all other countries, the funds may, if any, via "Private Placement" according to the local applicable laws.

It is explicitly stated, that alternative fund products are not allowed for public distribution in any country and that they may only and exclusively be solicited to institutional and qualified private investors according to the applicable local laws of each country.

The information and services provided on the sites are not intended for offer to or use by legal entities or natural persons in legal jurisdictions or countries in which the offer or use thereof would violate local legislation or legal provisions, or in which business units forming part of Bellevue Group would be subject to registration requirements in such jurisdictions or countries. Legal entities or natural persons to which such prohibitions apply must not access or use these sites.

The Bellevue funds have NOT been licensed for public offer or sale to the public in the United States in accordance with the US Investment Company Act of 1940 or the US Securities Act of 1933, or in Canada, Japan, Taiwan, Malaysia, Hong Kong or Israel in accordance with the laws in force in those countries. Therefore, particular importance is attached to ensuring that these sites are not intended for legal entities or natural persons, who have their registered office or who reside in such countries, their territories or dependencies or who, on account of their citizenship or similar status, are subject to the law of one of these countries.

Fund documents Luxembourg Fund

Bellevue SICAV: The Bellevue Funds (Lux) SICAV is admitted for public offering and distribution in Switzerland . Representative agent in Switzerland   Waystone Fund Services (Switzerland) SA, Avenue Villamont 17, CH-1005 Lausanne and paying agent in Switzerland: DZ PRIVATBANK (Schweiz) AG Münsterhof 12, PO Box, CH-8022 Zürich. Austria: Paying and information agent: Zeidler Legal Process Outsourcing Limited., 19-22 Lower Baggot Street, Dublin 2, D02 X658, Ireland. Germany: information agent: Zeidler Legal Process Outsourcing Limited., 19-22 Lower Baggot Street, Dublin 2, D02 X658, Ireland. Spain: The Bellevue Funds (Lux) SICAV is registered with the CNMV under the number 938. Paying and information agent: atl Capital, Calle de Montalbán 9, ES-28014 Madrid.  Prospectus, Key Investor Information Document (“KID”), the articles of association as well as the annual and semi - annual reports of the Bellevue Funds under Luxembourg law are available free of charge from the above mentioned representative, paying, facilities and information agents as well as from Bellevue Asset Management AG, Theaterstrasse 12, CH-8001 Zurich.

Bellevue Asset Management (Deutschland) GmbH: You can obtain the sales prospectus, the annual reports and the german key investor information documents free of charge from Bellevue Asset Management (Deutschland) GmbH, and also from banks and financial advisers. Paying agent in Switzerland is DZ PRIVATBANK (Schweiz) AG, Münsterhof 12, PO Box, CH-8022 Zurich. The swiss agent is IPConcept (Schweiz) AG, In Gassen 6, PO Box, CH-8022 Zurich. In Switzerland you can obtain sales prospectus, the annual reports and the german key investor information documents free of charge from the agent and also from the paying agent. 

Fund documents Bellevue Entrepreneur Switzerland

Prospectus, Key Investor Information Document („KID“), fund contract as well as the annual and semi - annual reports of the Bellevue Fund under Swiss law are available free of charge from: Switzerland : PMG Fonds Management AG, Dammstrasse 23, 6300 Zug or Bellevue Asset Management AG, Theaterstrasse 12, CH-8001 Zurich.

Fund documents Bellevue Funds and Bellevue Healthcare Strategy

Prospectus, Key Investor Information Document („KID“), fund contract as well as the annual and semi - annual reports of the Bellevue Medtech and Services fund established under Swiss law in the category "Other Funds for Traditional Investments" are available free of charge from : Switzerland : Swisscanto Fondsleitung AG, Bahnhofstrasse 9 , CH - 8001 Zürich or Bellevue Asset Management AG, Theaterstrasse 12, CH-8001 Zurich.

Fund documents StarCapital Multi Income and StarCapital Dynamic Bonds

Prospectus, the key information document ("PRIIP-KID"), the management regulations and the semi-annual and annual report are available free of charge in German from Bellevue Asset Management (Deutschland) GmbH, your advisor or intermediary, the paying agents, the relevant custodian bank or from the management company IPConcept (Luxembourg) S.A. (société anonyme), 4, rue Thomas Edison, L-1445 Luxembourg, Luxembourg, https://www.ipconcept.com. For information on opportunities and risks as well as tax information, please refer to the current detailed sales prospectus. Further information on investor rights can be found on the Management Company's website (https://www.ipconcept.com). The management company may decide to cancel the arrangements it has made for the distribution of the units of its collective investment undertakings in accordance with Article 93a of Directive 2009/65/EC and Article 32a of Directive 2011/61/EU.

Fund documents Bellevue Option Premium fund

Prospectus, the key information document ("PRIIP-KID"), and the semi-annual and annual reports are available free of charge in German from Bellevue Asset Management (Deutschland) GmbH, your advisor or intermediary, the paying agents, the responsible depositary (UBS Europe SE, Bockenheimer Landstrasse 2-4, D-60306 Frankfurt am Main) or from the management company Universal-Investment-Gesellschaft mbH, Theodor-Heuss-Allee 70, D-60486 Frankfurt am Main, https://www.universal-investment.com. For information on opportunities and risks as well as tax information, please refer to the current detailed sales prospectus. Further information on investor rights can be found on the Management Company's website (https://www.universal-investment.com). The management company may decide to cancel the arrangements it has made for the distribution of the units of its collective investment undertakings in accordance with Article 93a of Directive 2009/65/EC and Article 32a of Directive 2011/61/EU.

Data protection

By accessing this website you state that you agree with the data protection statement. If you do not agree with this statement you should refrain from accessing any further pages of this website. This statement may be updated at any time. We therefore recommend that you check this statement regularly.

Confirmation

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Bellevue Biotech (CH)

ISIN-No.: CH0113817065

YTD: -15.20%

Active share: 37.82

Anzahl Positionen: 50

Biotech sector with sustainable, strong sales and earnings growth thanks to high innovation level   

 Expiring patents of pharma companies lead to high M&A activity (patent cliff)

Valuations very attractive on historical average over the last 10 years

Indexed performance (as at: 11.04.2025)

NAV: CHF 2'801.59 (13.04.2025)


01 Jan 2010 - 01 Jan 2010
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AA-CHF
Benchmark

Rolling performance (11.04.2025)

AA-CHFBenchmark
13.04.2024 - 13.04.2025-11.61%-16.53%
13.04.2023 - 13.04.2024-3.21%2.66%
13.04.2022 - 13.04.2023-8.85%-3.84%
13.04.2021 - 13.04.2022-1.16%-7.52%

Annualized performance (11.04.2025)

AA-CHFBenchmark
1 year-11.61%-16.53%
3 years-7.96%-7.15%
5 years-0.71%-1.68%
10 years-2.94%-1.34%
Since Inception p.a.7.39%9.26%

Cumulative performance (11.04.2025)

AA-CHFBenchmark
1M-17.58%-18.23%
YTD-15.20%-18.35%
1 year-11.61%-16.53%
3 years-22.02%-19.96%
5 years-3.50%-8.10%
10 years-25.80%-12.66%
Since Inception181.42%261.43%

Annual performance

AA-CHFBenchmark
20246.84%6.69%
2023-9.12%-5.57%
2022-10.36%-9.88%
20214.39%2.31%

Investment Focus

The Bellevue Biotech fund focuses on the most promising companies in the biotechnology sector. The fund actively invests in 30 to 50 stocks that have met all of the stringent selection criteria applied by us. These are biotech companies that have specialized in areas such as immunology, virology, neurology, oncology, cardiology, endocrinology, etc. Geographically, the fund’s investments are concentrated in North America, Europe and Asia. The fund takes ESG factors into consideration while implementing the aforementioned investment objectives.Show moreShow less

Investment suitability & Risk

SRI

Low risk

High risk

The Fund’s investment objective is to generate attractive and competitive capital growth in the long term. It is therefore particularly suited to investors with an investment horizon of at least 5 years who want to selectively diversify their portfolio with investments in the biotechnology sector and who are willing to accept the equity risks typical of this sector.

General Information

Investment ManagerBellevue Asset Management AG
CustodianZürcher Kantonalbank
Fund AdministratorSwisscanto Fondsleitung AG
AuditorErnst & Young AG
Launch date15.10.2010
Year end closing30. Sep
NAV CalculationDaily "Forward Pricing"
Cut of time15:00 CET
Management Fee1.80%
Subscription Fee (max.)2.50%
Performance Fee10.00% (with High Water Mark)
ISIN numberCH0113817065
Valor number11381706
BloombergADGLBIA SW
WKNA1H7EV

Legal Information

Legal formInvestment funds under Swiss law
SFDR categoryArticle 8
Redemption periodDaily

Key data (31.03.2025, base currency CHF)

Beta0.90
Volatility20.46
Tracking error6.93
Active share37.82
Correlation0.95
Sharpe ratio0.02
Information ratio-0.16
Jensen's alpha-0.98
No. of positions50

Top 10 positions

Gilead Sciences
Vertex Pharmaceuticals
Amgen
Regeneron Pharmaceuticals
Astrazeneca
Alnylam Pharmaceuticals
Argenx
Sanofi
Biomarin Pharmaceuticals
Beigene
10.5%
9.7%
9.2%
6.3%
5.2%
4.0%
3.4%
2.9%
2.8%
2.6%

Market capitalization

0 - 1 bn
1 - 2 bn
2 - 5 bn
5 - 15 bn
15 - 20 bn
> 20 bn
Others
2.5%
4.1%
14.8%
13.7%
2.7%
60.9%
1.4%

Geographic breakdown

United States
Other
Netherlands
Switzerland
China
Cash
79.6%
6.4%
6.0%
3.8%
3.3%
0.9%

Breakdown by sector

Oncology
Orphan Diseases
Infectious Diseases
Pulmonary Diseases
Other
Autoimmune disease
Metabolic Diseases
Cash
35.6%
20.3%
18.0%
11.9%
5.8%
5.3%
2.4%
0.9%

Benefits

  • New innovative drugs are powering sustainable momentum in the biotech sector.
  • Attractively valued large cap biotechs.
  • Expiring pharmaceutical patents trigger a rise in M&A activity.
  • Focus on US biotech companies with strong growth potential.
  • Bellevue Healthcare team – top-performing pioneer in the management of healthcare portfolios.

Risks

  • The fund actively invests in equities. Equities are subject to strong price fluctuations and so are also exposed to the risk of price losses.
  • Biotech equities can be subject to sudden substantial price movements owing to market, sector or company factors.
  • The fund invests in foreign currencies, which means a corresponding degree of currency risk against the reference currency.
  • Investing in emerging markets entails the additional risk of political and social instability.
  • The fund may invest a proportion of its assets in financial instruments that might under certain circumstances have a relatively low level of liquidity, which can in turn affect the fund’s liquidity.

Global equities performed poorly in March 2025, with the MSCI World Index down 4.5%. Uncertainty regarding US trade tariffs, and fear that austerity could drive an economic slowdown, contributed to a negative equity market environment as investors were quick to price in a potential slower earnings growth environment. US tech stocks (Nasdaq 100; -7.6%) and small-cap US stocks (Russell 2000; -7.0%) came under significant pressure, while European indexes (e.g. Dax in USD; +2.2%) performed better. 

Healthcare (MSCI World Healthcare) outperformed global equities (MSCI World) in March by 213 bps. While the sector declined on an absolute basis (-2.3%), it proved to be a relatively safe haven. We see this as being in line with the sectors fundamentals, such as high margins, innovation, and inelastic demand for its products and services. While the defensive names in the sector remained solid, caution is leaving the more innovative names on the sidelines. Biotech performed poorly in the month (NBI; -6.0%), with further underperformance for the higher-growth smaller companies (XBI Biotech ETF; -8.6%). This subsector has suffered from increased regulatory risk driven by changes in leadership at the FDA.  

Healthcare services (+7.8%) was the best performing healthcare GICS industry, driven by supportive guidance commentary, and a lack of tariff exposure. Cost saving initiatives within the National Institute of Health has created some uncertainty regarding life science tools (-4.5%) earnings, which was the worst performing industry in the month. From a geographical point of view, Asian healthcare (+1.2%) performed best in March, followed by emerging markets (+1.1%). US (-1.8%) and particularly European (-4.5%) healthcare were disappointing in the month, with the difference being the strength of services in the US and weakness in Novo Nordisk shares. 

The Bellevue Global Biotech (CH) Fund (AA-shares: -4.1%, in USD) outperformed its healthcare index benchmark by 187 bps, benefiting from several positive clinical trial readouts. Among the portfolio holdings, the strongest relative performance came from Protagonist (+28.7%) following the positive data update for their oral IL-23 in psoriasis, as well as from Mineralys (+73.7%) after successful Phase III data in patients with persistent hypertension.   

The companies in our portfolio are working on technologies or products for novel treatment solutions. We are also invested in selected specialty pharma companies that offer high growth rates and moderate valuations. The Bellevue Biotech (CH) Fund is well-positioned to profit from the milestones that are expected to be reached in 2025. The regulatory environment favors the innovation coming out of biotech labs and the coronavirus crisis burnished the image of drug developers. Looming patent expiries coupled with large piles of cash suggest large biopharma companies will continue to hunt biotech companies over the next 18 months. Inexpensive small and mid caps with attractive pipeline candidates are obvious takeover targets. By 2030, products generating USD 183 bn in annual sales will lose their patent protection.

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  • Portfolio Manager

    Lukas Leu

    Dr Lukas Leu has been at Bellevue Asset Management since 2021. He is lead portfolio manager of the Bellevue Obesity Solutions fund and portfolio manager of the Bellevue Healthcare Diversified fund. He holds a PhD in biochemistry from the Swiss Federal Institute of Technology in Zurich. He previously worked as a research assistant at his alma mater and as an equity research analyst in the healthcare sector at Julius Baer.
  • Portfolio Manager

    Terence McManus

    Dr Terence McManus joined Bellevue Asset Management in 2022 and is lead portfolio manager of the funds Bellevue Diversified Healthcare, Bellevue Healthcare Strategy/Sustainable and portfolio manager of the Bellevue Obesity Solutions fund. Prior to this, he has 12 years of experience within healthcare-specific investing and analysis at Jefferies Investment Bank, Credit Suisse, Julius Baer and most recently at J. Safra Sarasin where he managed a sustainable health fund. Terence started his career as a scientist focused on drug discovery. He holds a PhD in Neuroscience from the University of Southampton, UK.
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